Some of the well-known variations include:

1. Multiplayer Snake: Allows multiple players to compete against each other in real-time.

2. 3D Snake: Adds a third dimension to the gameplay, offering a more immersive experience.

3. Snake vs. Block: Combines elements of Snake with Breakout-style gameplay where the snake must break through numbered blocks.

4. Snake on a Plane: A variation where the snake moves on a plane that wraps around both horizontally and vertically.

5. Snake with Power-Ups: Introduces power-ups that provide the snake with special abilities or effects.

6. Endless Snake: A mode where the snake never stops moving, and the challenge lies in avoiding obstacles.

7. Invisible Snake: The snake becomes invisible, making it more challenging to navigate.

These variations offer diverse gameplay experiences while retaining the core mechanics of the classic snake game.