Need to remove blood stains from your sheets? Wondering how to get blood out of sheets? Act quickly for best results. Start by soaking the affected area in cold water, then apply a mixture of hydrogen peroxide and dish soap directly onto the stain. Gently scrub the area and rinse with cold water. For tougher stains, try using enzyme-based cleaners or a paste made of baking soda and water. Wash the sheets in cold water and air dry to prevent setting the stain.